Factors associated with HBV virological breakthrough
نویسندگان
چکیده
منابع مشابه
On-treatment HBV DNA dynamics predict virological breakthrough in entecavir-treated HBeAg-positive chronic hepatitis B
BACKGROUND & AIMS Virological breakthrough (VBT) could be a manifestation of chronic hepatitis B (CHB) in patients treated with long-term nucleot(s)ide analogues. We aimed to determine the association of on-treatment serum hepatitis B virus (HBV) DNA with VBT in HBeAg-positive CHB patients receiving entecavir (ETV) treatment. METHODS A retrospective cohort study, including 162 consecutive pat...
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Objective: This study was aim to clarify the postoperative hepatitis B virus reactivation (PHR) and risk factors of PHR in hepatocellular carcinoma (HCC) patients with hepatitis B virus (HBV)-DNA levels less than the minimum. And to figure out the significance of antiviral therapy on liver function recovery after hepatectomy. Methods: A total of 74 HCC patients with preoperative HBV-DNA levels ...
متن کاملBaseline HBV DNA level is the most important factor associated with virologic breakthrough in chronic hepatitis B treated with lamivudine.
AIM To identify the factors associated with virologic breakthrough and to select a subgroup of patients who respond well to lamivudine without developing virologic breakthrough (VBT). METHODS Of 79 patients who had received lamivudine therapy for 9-57 mo, 34 were HBeAg-positive and 45 were HBeAg-negative, 24 developed virologic breakthrough and 55 did not. Clinical and virologic factors were ...
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Hepatitis B virus (HBV) infection is a global problem and a major risk factor for hepatocellular carcinoma (HCC). microRNAs (miRNAs) comprise a group of small noncoding RNAs regulating gene expression at the posttranslational level, thereby participating in fundamental biological processes, including cell proliferation, differentiation, and apoptosis. In this review, we summarize the roles of m...
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ژورنال
عنوان ژورنال: Antiviral therapy
سال: 2016
ISSN: 1359-6535
DOI: 10.3851/imp3087